• Tyme Announces Presentation of Clinical Data on SM-88 in Prostate Cancer at 2018 ASCO Genitourinary Cancers Symposium

    Source: Nasdaq GlobeNewswire / 04 Jan 2018 08:00:57   America/New_York

    • Mack Roach, M.D., FASCO, University of California, San Francisco, to present data from ongoing Phase II clinical trial

    NEW YORK, Jan. 04, 2018 (GLOBE NEWSWIRE) -- Tyme Technologies, Inc. (Nasdaq:TYME), a clinical-stage biotechnology company developing cancer therapeutics, today announced that data from the ongoing Phase II clinical trial of its lead therapy SM-88 in patients with non-metastatic biochemical recurrent prostate cancer will be presented by Mack Roach, M.D., FASCO, University of California, San Francisco, in a poster session at the 2018 American Society of Clinical Oncology (ASCO) Genitourinary Cancers Symposium, to be held Feb. 8-10, 2018, at the Moscone West Building in San Francisco, Calif.

    Details on the poster are as follows:

    Title: Phase II trial of SM 88 in non-metastatic biochemical recurrent prostate cancer
    Abstract Number:
    Poster Session:
    Poster Session A: Prostate Cancer
    Poster Board Number: H15
    Date / Time: Thursday, Feb. 8, 11:30 a.m. – 1 p.m., and 5:15 p.m. – 6:15 p.m. PST
    Location: Moscone West Building

    Additional information on the meeting can be found on the ASCO Genitourinary Cancers Symposium website: https://gucasym.org/.

    About SM-88

    SM-88 is a potential first-in-class combination therapy that utilizes a proprietary dysfunctional tyrosine derivative to interrupt the metabolic processes of cancer cells, breaking down the cells’ key defenses and making them vulnerable to oxidative stress and death. SM-88 has demonstrated efficacy in the treatment of multiple oncology indications, including breast and prostate cancer, without report of significant toxicity or serious adverse events.

    SM-88 is being evaluated in a Phase II clinical trial for prostate cancer (NCT02796898). A Phase II clinical trial in pancreatic cancer is planned for initiation in the first quarter of 2018.

    About Tyme

    Tyme Inc. is a clinical-stage biotechnology company developing cancer therapeutics that are intended to be broadly effective across tumor types and have low toxicity profiles. Unlike targeted therapies that attempt to regulate specific mutations within cancer, the Company’s therapeutic approach is designed to take advantage of a cancer cell’s innate metabolic weaknesses to compromise its defenses, leading to cell death through oxidative stress and exposure to the body’s natural immune system. Tyme’s lead clinical program, SM-88, is a first-in-class combination therapy in Phase II development for prostate cancer. The Company is preparing to initiate an additional Phase II clinical trial in pancreatic cancer in early 2018.

    For more information, visit www.tymeinc.com.

    Forward-Looking Statements/Disclosure Notice

    In addition to historical information, this press release contains forward-looking statements under the Private Securities Litigation Reform Act that involve substantial risks and uncertainties. Such forward-looking statements within this press release include, without limitation, statements regarding our drug candidates (including SM-88), their clinical potential and non-toxic safety profiles, our drug development plans and strategies, our completed studies, ongoing and planned clinical trials, preliminary data results and the therapeutic design and mechanisms of our drug candidates; and readers can identify forward-looking statements by sentences or passages involving the use of terms such as “anticipates,” “believes,” “designed,” “could,” “estimates,” “expects,” “intends,” “may,” “plans,” “potential,” “predicts,” “projects,” “should,” “would” and similar expressions intended to identify forward-looking statements. The forward-looking statements contained in this press release are based on management’s current expectations, which are subject to uncertainty, risks and changes in circumstances that are difficult to predict and many of which are outside of Tyme’s control. These statements involve known and unknown risks, uncertainties and other factors which may cause the Company’s actual results, performance or achievements to be materially different from any historical results and future results, performances or achievements expressed or implied by the forward-looking statements. These risks and uncertainties include, but are not limited to, uncertainties inherent in research and development, including the ability to achieve clinical study start and completion dates; the possibility of unfavorable study results, including unfavorable new clinical data and additional analyses of existing data; risks associated with early, initial data, including the risk that the final Phase II data analysis, final results of additional clinical trials, or both, may be different from the preliminary data analysis and may not support further clinical development; whether and when any applications or other submissions for SM-88 may be filed with regulatory authorities; whether and when regulatory authorities may approve any applications or submissions; decisions by regulatory authorities regarding labeling and other matters that could affect commercial availability of SM-88; competitive developments; and the factors described in the section captioned “Risk Factors” of Tyme’s Annual Report on Form 10-K filed with the U.S. Securities and Exchange Commission on June 12, 2017 and Quarterly Report on Form 10-Q filed with the U.S. Securities and Exchange Commission on November 3, 2017 (available at www.sec.gov). The data set forth in these updated analyses are not necessarily predictive of future patient or clinical data outcomes.

    The information contained in this press release is as of release date and Tyme assumes no obligation to update forward-looking statements contained in this release as a result of future events or developments.


    Tyme Inc.
    Jonathan Eckard
    Chief Scientific Affairs Officer

    ICR Healthcare
    Stephanie Carrington

    6 Degrees
    Sarah Hall

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